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The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver, and gallbladder). Digestion involves the breakdown of food into smaller and smaller components, until they can be absorbed and assimilated into the body.
The gastrointestinal wall of the gastrointestinal tract is made up of four layers of specialised tissue. From the inner cavity of the gut (the lumen) outwards, these are the mucosa, the submucosa, the muscular layer and the serosa or adventitia.
Extracellular digestion takes place within this central cavity, which is lined with the gastrodermis, the internal layer of epithelium. This cavity has only one opening to the outside that functions as both a mouth and an anus : waste and undigested matter is excreted through the mouth/anus, which can be described as an incomplete gut .
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The cephalic phase of digestion is the stage in which the stomach responds to the mere sight, smell, taste, or thought of food. About 20% of total acid secretion occurs before food enters the stomach.
It also plays a role in regulating gut microbiota, influencing digestion and overall health. The stomach is located between the esophagus and the small intestine . The pyloric sphincter controls the passage of partially digested food ( chyme ) from the stomach into the duodenum , the first and shortest part of the small intestine, where ...
Digestive enzymes take part in the chemical process of digestion, which follows the mechanical process of digestion. Food consists of macromolecules of proteins, carbohydrates, and fats that need to be broken down chemically by digestive enzymes in the mouth , stomach , pancreas , and duodenum , before being able to be absorbed into the ...
Since digestion occurs outside the cell, it is said to be extracellular. It takes place either in the lumen of the digestive system, in a gastric cavity or other digestive organ, or completely outside the body. During extracellular digestion, food is broken down outside the cell either mechanically or with acid by special molecules called enzymes.