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Acarbose is a starch blocker. It works by inhibiting alpha glucosidase, an intestinal enzyme that releases glucose from larger carbohydrates such as starch and sucrose. It is composed of an acarviosin moiety with a maltose at the reducing terminus. It can be degraded by a number of gut bacteria. [3]
Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat.
The Stillman diet is a high-protein, low-carbohydrate diet devised in 1967 by physician Irwin Maxwell Stillman (1896–1975). [1] It focusses mostly on the complete avoidance of both fats and carbohydrates, and requires at least eight glasses of water to be consumed every day.
Irwin was founded in 1885 in Martinsville, Ohio as the Irwin Auger Bit Company by Charles Irwin, a pharmacist. Irwin had bought the rights to a solid-center auger bit from a local blacksmith. [3] In 1924, another blacksmith, Danish immigrant William Petersen of DeWitt, Nebraska, invented the first locking pliers [4] and named them Vise-Grips. [5]
In the realms of toxicology and pathology, the Irwin screen is utilised to determine whether the subject(s) show adverse effects from a course of pharmaceutical treatment or environmental pollution. It is an observational methodology .
The 5-HT2c receptor agonist Fenfluramine (market names Pondimin, Ponderax and Adifax) was discovered in 1972 as a result of research performed to identify anorectic compounds lacking the effects of psycho-stimulants and sympathomimetic agents (such as amphetamines).