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In laboratory animal husbandry, there is a huge demand for animals that have been kept in disease free conditions and housed in barrier units such as individually ventilated cages. This is very important because when animals are used for scientific research, particularly drug-related research, the animals must provide accurate and valid results.
A laboratory mouse cage. Mice are either bred commercially, or raised in the laboratory. In the U.S., Class A breeders are licensed by the U.S. Department of Agriculture (USDA) to sell animals for research purposes, while Class B dealers are licensed to buy animals from "random sources" such as auctions, pound seizure, and newspaper ads.
Many laboratory animals, including mice and rats, are chronically stressed which can also negatively affect research outcomes and the ability to accurately extrapolate findings to humans. [32] [33] Researchers have also noted that many studies involving mice, rats and other rodents are poorly designed, leading to questionable findings.
A report from Seton Hall University describes the suspension of a faculty member after lab mice were forced to live ... to nine to 12 mice in each cage, well beyond the IACUC's standard of five ...
Albino mice at an illegal Reedley lab were kept in unsanitary, ‘terrible’ conditions. Reedley lab mice not subjected to experiments but suffered ‘inhumane’ conditions, vet says Skip to ...
Harlan Laboratories says it is "dedicated to the humane care and use of research animals". [7] The IACUC and the company's veterinary staff manage policies and procedures to ensure that all animal use is performed in accordance with government and industry standards.
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Mice are naturally cautious of rats, who may kill and consume them. This behaviour is known as muricide (cf. Muricidal test). [16] The mouse cage should be cleaned every week to prevent odour and disinfected only if a mouse has been unwell to prevent infection and disease. In the wild, mice are able to co-exist with other small rodent species. [17]