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Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
The case fatality rate ranges from less than 1% to 15%, [2] [20] [30] [35] depending on the virus and location. In China, where most cases are caused by Hantaan virus and Seoul virus, [7] the case fatality rate is about 2.89%. [39] In South Korea, the case fatality rate is 1–2%. [2] The global case fatality rate for Seoul virus is around 1%.
Prognosis for HPS is often poor. The case fatality rate of HPS ranges from 30% to 60%. [2] [4] [21] [27] Death usually occurs 2–10 days after the onset of illness [10] and occurs suddenly during the cardiopulmonary phase of illness. [2] [3] Andes virus infection has a case fatality rate of about 40%, and Sin Nombre virus a case fatality rate ...
The new disease was named "hantavirus pulmonary syndrome (HPS)". [ 4 ] [ 18 ] In 2012, a small outbreak occurred at Yosemite National Park in California and claimed the lives of three tourists out of ten infected.
The disease had a variety of names, so in 1982, the World Health Organization officially named it "hemorrhagic fever with renal syndrome". [6] [32] In 1985, this group of viruses were named "hantaviruses" after Hantaan virus, [29] and in 1987, the genus Hantavirus was established to accommodate them in the then-family Bunyaviridae. [1]
Andes virus was accepted as a species by the International Committee on Taxonomy of Viruses in 1999 and has undergone a series of changes to its species name, first changing to Andes hantavirus, then Andes orthohantavirus, and most recently to the current Orthohantavirus andesense.
The rest were from California, Texas, Louisiana, Idaho, Nevada, the Dakotas, and Montana. Around 40 of these cases had been confirmed by laboratory, with 25 deaths. [10] Through December 31, 48 cases were confirmed nationwide, with 27 deaths (56%). [19] Death rates were similar cross age, sex, and race, though most of the infected were male.
Although New World hantaviruses typically cause hantavirus pulmonary syndrome (HPS), either disease can involve the patient's kidneys or lungs. [19] [20] The virus can cause severe health issues and even death. HPS has a mortality rate of 38%. [21]