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Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...
The anti-TNF-α monoclonal antibody infliximab is a major biological therapy for inflammatory bowel disease. Biological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. [1]
Proctocolitis is a general term for inflammation of the rectum and colon. [1] Signs and symptoms ... Treatment Antibiotics, such as ...
Fecal calprotectin, a marker of colon inflammation, may be elevated. Computed tomography of the abdomen is not routinely necessary, but may show thickening or inflammation in the distal colon (sigmoid colon) with associated diverticulosis. Treatment may consist of antibiotics, aminosalicylates (mesalamine), or prednisone. In rare cases, surgery ...
A new study in Gut found that colon cancer tumors have an imbalance of inflammatory and anti-inflammatory lipids, which suggests that chronic inflammation could raise the risk of colorectal cancer.
The disease is classified by the extent of involvement, depending on how far the disease extends: [14] proctitis (rectal inflammation), left sided colitis (inflammation extending to descending colon), and extensive colitis (inflammation proximal to the descending colon). [19] Proctosigmoiditis describes inflammation of the rectum and sigmoid colon.