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Pigment dispersion syndrome (PDS) is an eye disorder that can lead to a form of glaucoma known as pigmentary glaucoma. It takes place when pigment cells slough off from the back of the iris and float around in the aqueous humor .
Fundus photographs are also used to document abnormalities of disease process affecting the eye, and/or to follow up on the progress of the eye condition/disease such as diabetes, age-macular degeneration (AMD), glaucoma, multiple sclerosis, and neoplasm of the choroid, cranial nerves, retinal or eyeball.
Medical signs that can be detected from observation of eye fundus (generally by funduscopy) include hemorrhages, exudates, cotton wool spots, blood vessel abnormalities (tortuosity, pulsation and new vessels) and pigmentation. [3] Arteriolar constriction, seen as "silver wiring", and vascular tortuosities are seen in hypertensive retinopathy.
Overproduction of pigment by these cells can block the trabecular meshwork through which fluid drains from the eye. The increased fluid in the eye leads to increased pressure, which can lead to glaucoma. In humans, this is sometimes known as pigment dispersion syndrome. [2]
Nd:YAG laser peripheral iridotomy (LPI) may be used in patients susceptible to or affected by angle closure glaucoma or pigment dispersion syndrome. During laser iridotomy, laser energy is used to make a small, full-thickness opening in the iris to equalize the pressure between the front and back of the iris, thus correcting any abnormal ...
Sampaolesi line is a sign which may be observed during a clinical eye examination. During gonioscopy (where the structures of the eye's anterior segment are examined), if an abundance of brown pigment is seen at or anterior to Schwalbe's line, a Sampaolesi line is said to be present.