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Drugs or pharmaceutical agents inducing ototoxicity are regarded as ototoxic medications. Anatomy of the human ear There is a wide range of ototoxic medications, for example, antibiotics , antimalarials , chemotherapeutic agents , non-steroidal anti-inflammatory drugs (NSAIDs) and loop diuretics . [ 2 ]
At high doses, quinine, aspirin and other salicylates may also cause high-pitch tinnitus and hearing loss in both ears, typically reversible upon discontinuation of the drug. [20] Erectile dysfunction medications may have the potential to cause hearing loss. [36] However the link between erectile dysfunction medications and hearing loss remains ...
Ototoxic drugs also may cause subjective tinnitus, as they may cause hearing loss, [15] or increase the damage done by exposure to loud noise. [39] This damage may occur even at doses not considered ototoxic. [40] More than 260 medications have been reported to cause tinnitus as a side effect. [41]
Hearing aids can mask or cover up the tinnitus, and many with hearing loss and tinnitus find relief by using hearing aids. [136] Though there is no cure or agreed-upon treatment for tinnitus, some drugs have been shown to provide temporary reduction of tinnitus. [ 137 ]
Some over-the-counter as well as prescription drugs and certain industrial chemicals are ototoxic. Exposure to these can result in temporary or permanent hearing loss. Some medications cause irreversible damage to the ear, and are limited in their use for this reason. The most important group is the aminoglycosides (main member gentamicin). A ...
Noise exposure is the cause of approximately half of all cases of hearing loss, causing some degree of problems in 5% of the population globally. [5] The National Institute for Occupational Safety and Health (NIOSH) recognizes that the majority of hearing loss is not due to age, but due to noise exposure.
Like other medications, finasteride went through several large-scale clinical trials before it received approval from the FDA (the federal gov body that assures the safety and efficacy of ...
Betahistine was once believed to have some positive effects in the treatment of Ménière's disease and vertigo, [3] but more recent evidence casts doubt on its efficacy. [4] [5] Studies of the use of betahistine have shown a reduction in symptoms of vertigo and, to a lesser extent, tinnitus, but conclusive evidence is lacking at present.