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Pseudoephedrine, the decongestant found in Sudafed, is highly effective in helping people with stuffy noses breathe more easily, said Dr. Maryann Amirshahi, a medical toxicologist and a professor ...
Propylhexedrine should not be used if a MAOI has been used in the past 14 days or is currently in use by a person. [2] Unlike other topical decongestants, propylhexedrine is not required to carry a warning against use in individuals with hypertension. [9] Propylhexedrine is not recommended in individuals younger than six years of age. [10]
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
Due to its sympathomimetic effects, pseudoephedrine is a vasoconstrictor and pressor agent (increases blood pressure), a positive chronotrope (increases heart rate), and a positive inotrope (increases force of heart contractions). [18] [1] [22] [19] [20] The influence of pseudoephedrine on blood pressure at clinical doses is controversial.
A popular over-the-counter decongestant ingredient doesn’t actually work, according to advisors to the FDA. CVS plans to pull some products containing popular decongestant from shelves.
Do over-the-counter decongestants like Sudafed PE work? Doctors have said oral phenylephrine is ineffective to relieve nasal congestion. An FDA panel will reevaluate the evidence.