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Doxylamine is generally safe for administration to healthy adults. Doses of doxylamine of up to 1,600 mg/day for 6 months have been given to adults with schizophrenia, with little toxicity encountered. [33] The median lethal dose (LD 50) is estimated to be 50–500 mg/kg in humans. [34]
It is an anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine is a potent single-dose agent for treatment of S. mansoni infection, and it causes worms to shift from the mesenteric veins to the liver, where the male worms are retained; the female worms return to the mesentery ...
The term dosage form may also sometimes refer only to the pharmaceutical formulation of a drug product's constituent substances, without considering its final configuration as a consumable product (e.g., capsule, patch, etc.). Due to the somewhat ambiguous nature and overlap of these terms within the pharmaceutical industry, caution is ...
UNOSOM (United Nations Operation in Somalia) may refer to: . UNOSOM I, an operation established in April 1992 and running until its duties were assumed by the UNITAF mission in December 1992
[3] [4] It is a fixed-dose combination of artesunate and amodiaquine. [3] Specifically it recommended for acute uncomplicated Plasmodium falciparum malaria. [5] It is taken by mouth. [4] Common side effects include loss of appetite, nausea, abdominal pain, sleepiness, trouble sleeping, and cough. [6]
In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. [1] The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.
Piperaquine is an antimalarial drug, a bisquinoline first made in the 1960s, and used extensively in China and Indochina as prophylaxis and treatment during the next 20 years. Usage declined in the 1980s as piperaquine-resistant strains of P. falciparum arose and artemisinin-based antimalarials became available.
The United Nations Operation in Somalia II (UNOSOM II) was the second phase of the United Nations intervention in Somalia and took place from March 1993 until March 1995, following the outbreak of the Somali Civil War in 1991.