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An adverse drug reaction (ADR) is a harmful, unintended result caused by taking medication. [1]: 1.1 Adverse Drug Reaction (ADR) [2] ADRs may occur following a single dose or prolonged administration of a drug or may result from the combination of two or more drugs.
Drug-drug interaction (DDI), an alteration of the action of a drug caused by the administration of other drugs; Paradoxical reaction, an effect of a substance opposite to what would usually be expected; Pharmacogenetics, the use of genetic information to determine which type of drugs will work best for a patient; Unintended consequences
Of these, 27 million have high-risk drug use—otherwise known as recurrent drug use—causing harm to their health, causing psychological problems, and or causing social problems that put them at risk of those dangers. [2] [3] In 2015, substance use disorders resulted in 307,400 deaths, up from 165,000 deaths in 1990.
Substance-induced psychosis (commonly known as toxic psychosis or drug-induced psychosis) is a form of psychosis that is attributed to substance intoxication, withdrawal or recent consumption of psychoactive drugs. It is a psychosis that results from the effects of various substances, such as medicinal and nonmedicinal substances, legal and ...
Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death.
At high doses, prescription amphetamines, used to treat ADHD could increase a person’s risk of psychosis. Image credit: visualspace/Getty Images.
Rhabdomyolysis associated with statins (anticholesterol drugs) [36] Seizures caused by withdrawal from benzodiazepines [37] Drowsiness or increase in appetite due to antihistamine use. Some antihistamines are used in sleep aids explicitly because they cause drowsiness. [38] Stroke or heart attack associated with sildenafil (Viagra), when used ...
A new study suggests that GLP-1 agonist medications like Ozempic, which are used for diabetes management and weight loss, may help reduce the risk of overdose and alcohol intoxication in people ...