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Phenylephrine is used as an eye drop to dilate the pupil to facilitate visualization of the retina. It is often used in combination with tropicamide as a synergist when tropicamide alone is not sufficient. Narrow-angle glaucoma is a contraindication to phenylephrine use. As a mydriatic, it is available in 2.5% and 10% eye drops.
The concern goes beyond ineffectiveness; phenylephrine can come with side effects such as headaches, insomnia and nervousness. At higher doses, it can increase blood pressure.
As Yahoo Life reported last year, when taken in oral form, phenylephrine is metabolized so quickly that the amount absorbed into the bloodstream ends up being less than 1% of what was originally ...
Amirshahi noted that pseudoephedrine comes with side effects, including dizziness, nervousness and trouble sleeping. It may also increase blood pressure, a potential drawback for people with heart ...
Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils. [15] Atropine degrades slowly, typically wearing off in 7 to 14 days, so it is generally used as a therapeutic mydriatic, whereas tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) is preferred as an aid to ...
Anticholinergic. Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system. [1][2] These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells.
The stakes are high, experts say, because a committee vote declaring phenylephrine ineffective as an oral decongestant could push the FDA to revoke the drug’s over-the-counter designation as ...
Phenylephrine is an oral medication primarily used as a decongestant. [5] [6] It is a selective α 1-adrenergic receptor activator which results in the constriction of both arteries and veins. [5] Common side effects include nausea, headache, and anxiety. [5] Phenylephrine was patented in 1927 and came into medical use in 1938. [7]