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The typical steps in metastasis are local invasion, intravasation into the blood or lymph, circulation through the body, extravasation into the new tissue, proliferation and angiogenesis. Different types of cancers tend to metastasize to particular organs, but overall the most common places for metastases to occur are the lungs , liver , brain ...
Typically, pancreatic adenocarcinoma first spreads to nearby lymph nodes, and later to the liver or to the peritoneal cavity, large intestine, or lungs. [3] Uncommonly, it spreads to the bones or brain. [37] Cancers in the pancreas may also be secondary cancers that have spread from other parts of the body. This is uncommon, found in only about ...