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  2. DNA construct - Wikipedia

    en.wikipedia.org/wiki/DNA_construct

    A DNA construct is an artificially-designed segment of DNA borne on a vector that can be used to incorporate genetic material into a target tissue or cell. [1] A DNA construct contains a DNA insert, called a transgene , delivered via a transformation vector which allows the insert sequence to be replicated and/or expressed in the target cell.

  3. Vector (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Vector_(molecular_biology)

    The vector itself generally carries a DNA sequence that consists of an insert (in this case the transgene) and a larger sequence that serves as the "backbone" of the vector. The purpose of a vector which transfers genetic information to another cell is typically to isolate, multiply, or express the insert in the target cell.

  4. Molecular Structure of Nucleic Acids: A Structure for ...

    en.wikipedia.org/wiki/Molecular_Structure_of...

    The two base-pair complementary chains of the DNA molecule allow replication of the genetic instructions. The "specific pairing" is a key feature of the Watson and Crick model of DNA, the pairing of nucleotide subunits. [5] In DNA, the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine. The A:T and C:G pairs ...

  5. Molecular models of DNA - Wikipedia

    en.wikipedia.org/wiki/Molecular_models_of_DNA

    Here, individual DNA tiles (model at left) self-assemble into a highly ordered DNA 2D-nanogrid (AFM image at right). There are various uses of DNA molecular modeling in Genomics and Biotechnology research applications, from DNA repair to PCR and DNA nanostructures. Two-dimensional DNA junction arrays have been visualized by Atomic force microscopy.

  6. Artificial gene synthesis - Wikipedia

    en.wikipedia.org/wiki/Artificial_gene_synthesis

    As DNA printing and DNA assembly methods have allowed commercial gene synthesis to become progressively and exponentially cheaper over the past years, [50] artificial gene synthesis represents a powerful and flexible engineering tool for creating and designing new DNA sequences and protein functions.

  7. Vector quantity - Wikipedia

    en.wikipedia.org/wiki/Vector_quantity

    A free vector is a vector quantity having an undefined support or region of application; it can be freely translated with no consequences; a displacement vector is a prototypical example of free vector. Aside from the notion of units and support, physical vector quantities may also differ from Euclidean vectors in terms of metric.

  8. Expression vector - Wikipedia

    en.wikipedia.org/wiki/Expression_vector

    An expression vector, otherwise known as an expression construct, is usually a plasmid or virus designed for gene expression in cells. The vector is used to introduce a specific gene into a target cell, and can commandeer the cell's mechanism for protein synthesis to produce the protein encoded by the gene.

  9. Bacterial artificial chromosome - Wikipedia

    en.wikipedia.org/wiki/Bacterial_artificial...

    A bacterial artificial chromosome (BAC) is a DNA construct, based on a functional fertility plasmid (or F-plasmid), used for transforming and cloning in bacteria, usually E. coli. [ 1 ] [ 2 ] [ 3 ] F-plasmids play a crucial role because they contain partition genes that promote the even distribution of plasmids after bacterial cell division.

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