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Daratumumab, sold under the brand name Darzalex among others, is an anti-cancer monoclonal antibody medication. It binds to CD38 , [ 7 ] which is overexpressed in multiple myeloma cells. [ 8 ]
It was approved for use in the United States in May 2020. [2] [7] [8]Efficacy of daratumumab and hyaluronidase-fihji (monotherapy) was evaluated in the COLUMBA trial (NCT03277105), an open-label non-inferiority trial randomizing 263 participants to daratumumab and hyaluronidase-fihj and 259 to intravenous daratumumab (daratumumab IV). [2]
Daratumumab [1] Janssen Biotech: multiple myeloma: Nivolumab [1] Bristol-Myers Squibb: advanced renal cell carcinoma: Elotuzumab [1] Bristol-Myers Squibb: multiple myeloma: Sebelipase alfa [1] Alexion Pharmaceuticals: lysosomal acid lipase deficiency: Alectinib [1] Hoffmann-La Roche: ALK-mutated NSCLC: Pembrolizumab [1] Merck Sharp & Dohme ...
treatments work best6! Reduce use of inefficient and ineffective treatments6! Devise systems to pay doctors for results, as opposed to current fee-for-service system10! Establish a non-profit or public organization, (perhaps within IOM), to research and compile best methods of providing health care10 ¥ Will evaluate devices and drugs, compare
Octomom Natalie Suleman is ready to bring her story to the screen. The 49-year-old single mom of 14 — who made history as the first person to give birth to surviving octuplets in 2009 — is the ...
It works on all hair colors and skin tones: Unlike laser hair removal, electrolysis doesn't rely on melanin or pigment, making it an effective option for even the lightest hair colors. “If you ...
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