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Starved for oxygen and nutrients, elastic fibers become patchy and smooth muscle cells die. If the disease progresses, syphilitic aortitis leads to an aortic aneurysm. Overall, tertiary syphilis is a rare cause of aortic aneurysms. [3] Syphilitic aortitis has become rare in the developed world with the advent of penicillin treatments after ...
Aortitis is most commonly seen in patients with syphilis, autoimmune vasculitis (giant cell arteritis, Takayasu's arteritis), polymyalgia rheumatica, and rheumatoid arthritis. [2] IgG4-related disease has more recently been identified as a cause of aortitis, and also as a cause of periaortitis (inflammation surrounding the aorta).
The most common complication is syphilitic aortitis, which may result in aortic aneurysm formation. [3] Neurosyphilis refers to an infection involving the central nervous system. Involvement of the central nervous system in syphilis (either asymptomatic or symptomatic) can occur at any stage of the infection. [21]
Cor bovinum or cor bovis refers to a massive hypertrophy of the left ventricle of the heart due to volume overload, usually in earlier times in the context of tertiary syphilis but currently more often due to chronic aortic regurgitation, hypertensive and ischaemic heart disease.
Pages in category "Syphilis" The following 47 pages are in this category, out of 47 total. ... Syphilitic aortitis; T. Tabes dorsalis; Terre Haute prison experiments;
In 1899 Heller proved that syphilis was a cause of aortic aneurysm, and with his assistant Karl Gottfried Paul Döhle (1855-1928), he described syphilitic aortitis, a condition sometimes referred to as "Döhle-Heller syndrome". In 1869 he demonstrated how lymph propulsion takes place in the lymph vessels.
However, mycotic aneurysm is still used for all extracardiac or intracardiac aneurysms caused by infections, except for syphilitic aortitis. [ 6 ] The term "infected aneurysm" proposed by Jarrett and associates [ 7 ] is more appropriate, since few infections involve fungi . [ 8 ]
In terms of the cause of aortic regurgitation, is often due to the aortic root dilation (annuloaortic ectasia), which is idiopathic in over 80% of cases, but otherwise may result from aging, syphilitic aortitis, osteogenesis imperfecta, aortic dissection, Behçet's disease, reactive arthritis and systemic hypertension. [1]