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There is likely little or no effect of a BRCA gene mutation on overall fertility, [19] although women with a BRCA mutation may be more likely to have primary ovarian insufficiency. [20] [21] BRCA mutation carriers may be more likely to give birth to girls than boys, [22] however this observation has been attributed to ascertainment bias. [23] [24]
Quest Diagnostics is challenging Myriad Genetics stranglehold on the BRCA1 and BRCA2 cancer testing market. Quest announced that it's rolling out a cheaper alternative in hopes of winning share in ...
Home genetic test kits from 23andMe may detect some important BRCA gene mutations that can increase your risk for breast cancer. Here's what to know before you test.
672 12189 Ensembl ENSG00000012048 ENSMUSG00000017146 UniProt P38398 P48754 RefSeq (mRNA) NM_007294 NM_007295 NM_007296 NM_007297 NM_007298 NM_007299 NM_007300 NM_007301 NM_007302 NM_007303 NM_007305 NM_007306 NM_009764 RefSeq (protein) NP_009225 NP_009228 NP_009229 NP_009230 NP_009231 NP_033894 Location (UCSC) Chr 17: 43.04 – 43.17 Mb Chr 11: 101.38 – 101.44 Mb PubMed search Wikidata View ...
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Prophylactic salpingo-oophorectomy (removal of the ovaries and fallopian tubes to prevent cancer) is recommended at age 35-40 for people with BRCA1 mutations and at age 40-45 for people with BRCA2 mutations. [6] An increasing number women who test positive for faulty BRCA1 or BRCA2 genes choose to have risk-reducing surgery. At the same time ...
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