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Serious side effects may include angioedema, low blood sugar, kidney problems, pancreatitis, and joint pain. [8] Whether use in pregnancy or breastfeeding is safe is unclear. [ 10 ] It is in the dipeptidyl peptidase-4 (DPP-4) inhibitor class and works by increasing the production of insulin and decreasing the production of glucagon by the pancreas.
Diabetes medications have four main mechanisms of action: [citation needed] Insulin sensitization: Increased sensitivity of insulin receptors on cells leading to decreased insulin resistance, and higher effects of insulin on blood glucose levels. Stimulation of beta cells: This stimulation increases insulin secretion from beta cells of pancreas.
Compressed air dryers are special types of filter systems that are specifically designed to remove the water that is inherent in compressed air. The compression of air raises its temperature and concentrates atmospheric contaminants, primarily water vapor, as resulting in air with elevated temperature and 100% relative humidity.
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Despite guidelines recommending that intensive blood sugar control be based on balancing immediate harms with long-term benefits, many people – for example people with a life expectancy of less than nine years who will not benefit, are over-treated. [103] It is recommended that all people with type 2 diabetes get regular eye examinations. [13]
Adverse effects include nasopharyngitis, headache, nausea, heart failure, hypersensitivity and skin reactions. [ citation needed ] The U.S. Food and Drug Administration (FDA) is warning that the type 2 diabetes medicines like sitagliptin , saxagliptin , linagliptin , and alogliptin may cause joint pain that can be severe and disabling.