Ads
related to: pyrantel pamoate wikipedia
Search results
Results From The WOW.Com Content Network
Pyrantel pamoate acts as a depolarizing neuromuscular blocking agent, thereby causing sudden contraction, followed by paralysis, of the helminths.This has the result of causing the worm to "lose its grip" on the intestinal wall and be passed out of the system by natural process.
Pyrantel pamoate (also called pyrantel embonate, brand names e.g., Reese's Pinworm Medicine, Pin-X, Combantrin, Anthel, Helmintox, and Helmex) kills adult pinworms through neuromuscular blockade, [27] and is considered as effective as the benzimidazole compounds and is used as a second-line medication. [9]
Pyrantel pamoate (Antiminth, Pin-Rid, Pin-X), depolarizes ganglionic block of nicotinic neuromuscular transmission, resulting in spastic paralysis of the worm. Spastic (tetanic) paralyzing agents, in particular pyrantel pamoate, may induce complete intestinal obstruction in a heavy worm load. Dosage is 11 mg/kg not to exceed 1 g as a single dose.
Contact Wikipedia; Code of Conduct; Developers; Statistics; Cookie statement; Mobile view; Search. Search. Toggle the table of contents. List of drugs used to treat ...
Pyrantel pamoate – effective against most parasitic nematodes of the GIT; Macrocyclic lactones are glutamate-gated chloride channel agonists, [8] and include: Avermectins (including ivermectin and moxidectin) - effective against most common intestinal worms, except tapeworms, for which praziquantel is commonly used in conjunction for mass ...
Pharmaceutical drugs formulated this way include cycloguanil pamoate, hydroxyzine pamoate, imipramine pamoate, olanzapine pamoate hydrate, oxantel pamoate, pyrantel pamoate, and pyrvinium pamoate. Pamoic acid has agonist activity for the orphan G protein-coupled receptor GPR35 by which it activates ERK and beta-arrestin2 , and causes ...