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Cell excitability is the change in membrane potential that is necessary for cellular responses in various tissues. The resting potential forms the basis of cell excitability and these processes are fundamental for the generation of graded and action potentials. Normal and pathological activities in the heart and brain can be modelled as ...
These experiments have furthermore opened new avenues for preventative drug efficacy. Measurement of chronaxie and rheobase in sural sensory fibers has revealed mild reductions in excitability in diabetics, as evidenced by significant reductions in conduction velocity and chronaxie of sensory fibers with corresponding increases in rheobase. [ 6 ]
The neurotransmitter most often associated with EPSPs is the amino acid glutamate, and is the main excitatory neurotransmitter in the central nervous system of vertebrates. [2]
Chronaxie is the tissue-excitability parameter that permits choice of the optimum stimulus pulse duration for stimulation of any excitable tissue. Chronaxie (c) is the Lapicque descriptor of the stimulus pulse duration for a current of twice rheobasic (b) strength, which is the threshold current for an infinitely long-duration stimulus pulse.
Basic ways that neurons can interact with each other when converting input to output. Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs ...
In neurons that are involved in chemical synaptic transmission, neurotransmitters are synthesized either in the neuronal cell body, or within the presynaptic terminal, depending on the type of neurotransmitter being synthesized and the location of enzymes involved in its synthesis.
Vertiginous question: Why is it that a specific subject of experience is "live" from a given perspective? What, if anything, is the function of consciousness? [2] [3] Problem of mental causation: How exactly do mental states cause intentional actions to happen? What is the nature and mechanism behind near-death experiences? How can death be ...
Design of Experiments: A systematic, rigorous approach to engineering problem-solving that applies principles and techniques at the data collection stage so as to ensure the generation of valid, defensible, and supportable engineering conclusions [1] Design Point: A single combination of settings for the independent variables of an experiment.