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Stress can cause acute and chronic changes in certain brain areas which can cause long-term damage. [4] Over-secretion of stress hormones most frequently impairs long-term delayed recall memory, but can enhance short-term, immediate recall memory. This enhancement is particularly relative in emotional memory.
Difficulty creating recent term memories is called anterograde amnesia and is caused by damage to the hippocampus part of the brain, which is a major part of the memory process. [8] Retrograde amnesia is also caused by damage to the hippocampus, but the memories that were encoded or in the process of being encoded in long-term memory are erased [8]
Further research has revealed that the protein kinase A (PKA) signaling pathway is crucial to long-term memory. If PKA or protein synthesis inhibition occurs at certain moments during sleep, memory consolidation can be disrupted [citation needed]. In addition, mice with genetic inhibition of PKA have been shown to have long-term memory deficits ...
The enhancing effects of emotional arousal on later memory recall tend to be maintained among older adults and the amygdala shows relatively less decline than many other brain regions. [75] However, older adults also show somewhat of a shift towards favoring positive over negative information in memory, leading to a positivity effect.
Issues in memory can also be linked to several common physical and psychological causes, such as: anxiety, dehydration, depression, infections, medication side effects, poor nutrition, vitamin B12 deficiency, psychological stress, substance abuse, chronic alcoholism, thyroid imbalances, and blood clots in the brain.
[23] [24] For instance, studies have also shown a relationship between depression and its cognitive effects on everyday functioning and distortions of memory. [25] Since pseudodementia does not cause deterioration of the brain, brain scans can be used to visualize potential deterioration associated with dementia.
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