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An estrogen-dependent condition can be that relating to the differentiation in the steroid sex hormone that is associated with the female reproductive system and sex characteristics. [1] These conditions can fall under the umbrella of hypoestrogenism, hyperestrogenim, or any sensitivity to the presence of estrogen in the body.
Upon menopause in females, production of estrogens by the ovaries stops and estradiol levels decrease to very low levels. In addition to its role as a natural hormone, estradiol is used as a medication , for instance in menopausal hormone therapy and feminizing hormone therapy for transgender women ; for information on estradiol as a medication ...
[10] [15] During normal human pregnancy, estrogen production increases progressively and extremely high estrogen levels are attained. [19] Estradiol levels range from 1,000 to 40,000 pg/mL across pregnancy, [20] are on average 25,000 pg/mL at term, and reach levels as high as 75,000 pg/mL in some women. [21
The four major naturally occurring estrogens in women are estrone (E1), estradiol (E2), estriol (E3), and estetrol (E4). Estradiol (E2) is the predominant estrogen during reproductive years both in terms of absolute serum levels as well as in terms of estrogenic activity.
The stages of the menopause transition have been classified according to a woman's reported bleeding pattern, supported by changes in the pituitary follicle-stimulating hormone (FSH) levels. [57] In younger women, during a normal menstrual cycle the ovaries produce estradiol, testosterone and progesterone in a cyclical pattern under the control ...
Estrogen levels were dramatically and persistently elevated (estradiol levels were 2,340 pg/mL, regarded as being about 10 times the normal level, and ranged from 750 to 3,500 pg/mL), gonadotropin levels were mildly elevated (follicle-stimulating hormone and luteinizing hormone levels were 6.7–19.1 mIU/mL and 5.8–13.2 mIU/mL, respectively ...