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The four major naturally occurring estrogens in women are estrone (E1), estradiol (E2), estriol (E3), and estetrol (E4). Estradiol (E2) is the predominant estrogen during reproductive years both in terms of absolute serum levels as well as in terms of estrogenic activity.
Upon menopause in females, production of estrogens by the ovaries stops and estradiol levels decrease to very low levels. In addition to its role as a natural hormone, estradiol is used as a medication , for instance in menopausal hormone therapy and feminizing hormone therapy for transgender women ; for information on estradiol as a medication ...
If you’re expecting, your estrogen levels naturally rise during pregnancy, says Dr. Woo. In particular, estriol increases during pregnancy to support fetal development and prepare the body for ...
Pre-menopausal women have higher levels of hormones including estrogen. After menopause, estrogenic fat diminishes, and lower levels of both estradiol and estrone are found in breast adipocytes, with a more pronounced decrease in estradiol levels. [3]
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[10] [15] During normal human pregnancy, estrogen production increases progressively and extremely high estrogen levels are attained. [19] Estradiol levels range from 1,000 to 40,000 pg/mL across pregnancy, [20] are on average 25,000 pg/mL at term, and reach levels as high as 75,000 pg/mL in some women. [21