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Hepatomegaly is enlargement of the liver. [4] It is a non-specific medical sign , having many causes, which can broadly be broken down into infection , hepatic tumours , and metabolic disorder . Often, hepatomegaly presents as an abdominal mass .
Hepatomegaly Medical imaging : Longitudinal axis > 15.5 cm at the hepatic midline, or > 16.0 cm at the midclavicular line [ 14 ] Autopsy : Weight over upper limit of standard reference range, of 1,860 g (4.10 lb) in men [ 12 ] and 1,770 g (3.90 lb) in women.
Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.
Using this more inclusive definition, the global prevalence of MAFLD is an astonishingly high 50.7%. [40] Indeed, also using the old NAFLD definition, the disease is observed in up to 80% of obese people, 35% of whom progress to NASH, [ 41 ] and in up to 20% of normal weight people, [ 10 ] despite no evidence of excessive alcohol consumption.
[17] 10–20% of people will also experience an enlarged spleen, while some people will also experience a mild unintentional weight loss. [ 17 ] [ 19 ] The recovery phase is characterized by resolution of the clinical symptoms of hepatitis with persistent elevations in liver lab values and potentially a persistently enlarged liver. [ 17 ]
The liver span is a measurement performed during physical examination to determine the size of the liver and identify possible hepatomegaly.. It is the distance between the lower border of the liver in the mid-clavicular line obtained by palpation, and the upper border of the liver in the mid-clavicular line detected by percussion (the upper border of the liver lies behind the ribs and can not ...
Signs and symptoms of liver masses vary from being asymptomatic to patients presenting with an abdominal mass, hepatomegaly, abdominal pain, jaundice, or some other liver dysfunction. Treatment varies and is highly specific to the type of liver tumor. [3]
Signs and symptoms depend largely upon the primary lesions giving rise to the condition. In addition to the heart or lung symptoms, there will be a sense of fullness and tenderness in the right hypochondriac region.