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It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well for osteoporosis in combination with other medications. [ 1 ] [ 2 ] In 2022, the combination, calcium/vitamin D was the 246th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
From amphibians onward, bone management is biodynamic, with bone functioning as internal calcium reservoir under the control of osteoclasts via the combined action of parathyroid hormone and 1α,25-dihydroxyvitamin D 3 Thus, the vitamin D story started as inert molecule but gained an essential role for calcium and bone homeostasis in ...
Sam's Choice, originally introduced as Sam's American Choice in 1991, is a retail brand in food and selected hard goods. Named after Sam Walton, founder of Walmart, Sam's Choice forms the premium tier of Walmart's two-tiered core corporate grocery branding strategy that also includes the larger Great Value brand of discount-priced staple items.
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[8] [9] It is also used in the management of familial hypophosphatemia, hypoparathyroidism that is causing low blood calcium, and Fanconi syndrome. [9] [10] Vitamin-D supplements may not be effective in people with severe kidney disease. [11] [10] Excessive doses in humans can result in vomiting, constipation, muscle weakness, and confusion. [5]
The hard ions such as calcium (Ca 2+) and magnesium (Mg 2+) adhere to the sulfonate groups, displacing sodium ions. The resulting solution of sodium ions is softened. Idealized image of water softening process involving replacement of calcium ions in water with sodium ions donated by a cation exchange resin.