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Chlorphenamine is the INN Tooltip International Nonproprietary Name while chlorpheniramine is the USAN Tooltip United States Adopted Name and former BAN Tooltip British Approved Name. Brand names include Chlor-Trimeton, Demazin, Allerest 12 Hour, Piriton, Chlorphen-12, Tylenol Cold/Allergy, and numerous others according to country. [2]
Chlorphenamine (Piriton), a less sedating antihistamine, was synthesized in 1951, and hydroxyzine (Atarax, Vistaril), an antihistamine used specifically as a sedative and tranquilizer, was developed in 1956. [22] [26] The first non-sedating antihistamine was terfenadine (Seldane) and was developed in 1973.
This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it.
H 1 antagonists, also called H 1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic action but are not true antihistamines.
It is often sold as a maleate salt, pyrilamine maleate. The medication has negligible anticholinergic activity, with 130,000-fold selectivity for the histamine H 1 receptor over the muscarinic acetylcholine receptors (for comparison, diphenhydramine had 20-fold selectivity for the H 1 receptor). [3] It was patented in 1943 and came into medical ...
Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine.
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