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Stelazine (trifluoperazine) – an antipsychotic used in the treatment of psychotic disorders, anxiety, and nausea caused by chemotherapy [2] Strattera (atomoxetine) – a non-stimulant medication used to treat ADHD; Suboxone (buprenorphine/naloxone) - a partial opioid agonist used in the treatment of opioid use disorder
Lormetazepam is considered a hypnotic benzodiazepine and is officially indicated for moderate-to-severe insomnia.Lormetazepam is a short-acting benzodiazepine and is sometimes used in patients who have difficulty in maintaining sleep or falling asleep.
Mexazolam [1] (marketed under the trade names Melex and Sedoxil) [2] is a drug which is a benzodiazepine derivative. [3] Mexazolam has been trialed for anxiety and was found to be effective in alleviating anxiety at one week follow-up.
The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.
A review of clonazepam in the treatment of psychiatric disorders concluded that there is longitudinal data supporting anxiolytic benefit without tolerance during long-term use, [43] including an open-label study finding continued benefit at 3 years. [45] However, the review concludes that long-term RCT evidence is scant. A study of ...
The introduction of these drugs brought profound changes to the treatment of mental illness. It meant that more patients could be treated without the need for confinement in a psychiatric hospital . It was one of the key reasons why many countries moved towards deinstitutionalization , closing many of these hospitals so that patients could be ...
Although anxiety can temporarily increase as a withdrawal symptom, there is evidence that a reduction or withdrawal from benzodiazepines can lead to a reduction of anxiety symptoms in the long run. [4] [5] Due to these increasing physical and mental symptoms from long-term use of benzodiazepines, slow withdrawal is recommended for long-term users.
Both of them are considered as first-line anti-anxiety medications. TCAs are second-line treatment as they cause more significant adverse effects when compared to the first-line treatment. Benzodiazepines are effective in emergent and short-term treatment of anxiety disorders due to their fast onset but carry the risk of dependence. [4]