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Hyperchloremia is an electrolyte disturbance in which there is an elevated level of chloride ions in the blood. [1] The normal serum range for chloride is 96 to 106 mEq/L , [ 2 ] therefore chloride levels at or above 110 mEq/L usually indicate kidney dysfunction as it is a regulator of chloride concentration. [ 3 ]
Severity of symptoms is directly correlated with severity of hyponatremia and rapidness of onset. [3] General symptoms include loss of appetite, nausea, vomiting, confusion, agitation, and weakness. [14] [3] More concerning symptoms involve the central nervous system and include seizures, coma, and death due to brain herniation.
Analysis of accuracy has shown promise in DXplain and similar clinical decision support systems. In a preliminary trial investigation of 46 benchmark cases with a variety of diseases and clinical manifestations, the ranked differential diagnoses generated by DXplain were shown to be in alignment with a panel of five board-certified physicians ...
The Medical Research Council (MRC) Laboratory of Medical Sciences (LMS) (formerly MRC Clinical Sciences Centre, and then the MRC London Institute of Medical Sciences) is a biomedical research institute based in West London, UK. Research at the institute focuses on the understanding of the molecular and physiological basis of health and disease.
National Center for Research Resources; National Centers for Biomedical Computing; National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; National Institute on Deafness and Other Communication Disorders; National Institute on Minority Health and Health Disparities; National Wilms Tumor Study Group
The diagnosis may be suspected based on symptoms and MRI and confirmed by tissue biopsy. [6] [7] Blood tests may show anaemia, and less commonly a low white blood cell count and low platelet count. [5] Treatment may involve surgery, chemotherapy, radiation therapy, and certain medicines. [7]
Institut de recherches cliniques de Montréal (IRCM), (also known, in English, as Montreal Clinical Research Institute), is a medical research institute affiliated with Université de Montréal. Its work focuses mainly on cellular biology, molecular biology, genetics, developmental biology, and proteomics. Its aim is to understand the causes of ...
Renal tubular acidosis (RTA) is a medical condition that involves an accumulation of acid in the body due to a failure of the kidneys to appropriately acidify the urine. [1] In renal physiology, when blood is filtered by the kidney, the filtrate passes through the tubules of the nephron, allowing for exchange of salts, acid equivalents, and other solutes before it drains into the bladder as urine.