Search results
Results From The WOW.Com Content Network
Since, aldehydes reduce more easily than ketones, they require milder reagents and milder conditions. At the other extreme, carboxylic acids, amides, and esters are poorly electrophilic and require strong reducing agents. [17] The idealized equation for the reduction of a ketone by sodium borohydride is: 4 RCOR' + NaBH 4 → NaB(OCHRR') 4
Sodium borohydride, also known as sodium tetrahydridoborate and sodium tetrahydroborate, [5] is an inorganic compound with the formula Na B H 4 (sometimes written as Na[BH 4]). It is a white crystalline solid, usually encountered as an aqueous basic solution. Sodium borohydride is a reducing agent that finds application in papermaking and dye ...
At low pH values, it efficiently reduces aldehydes and ketones. [7] As the pH increases, the reduction rate slows and instead, the imine intermediate becomes preferential for reduction. [7] For this reason, NaBH 3 CN is an ideal reducing agent for one-pot direct reductive amination reactions that don't isolate the intermediate imine. [2]
Sodium triacetoxyborohydride is a milder reducing agent than sodium borohydride or even sodium cyanoborohydride. It reduces aldehydes but not most ketones. It is especially suitable for reductive aminations of aldehydes and ketones. [2] [3] [4]
The Meyers synthesis is an organic synthesis for the preparation of unsymmetrical aldehydes ... sodium borohydride ... water and oxalic acid to the aldehyde. ...
Luche reduction is the selective organic reduction of α,β-unsaturated ketones to allylic alcohols. [ 1 ] [ 2 ] [ 3 ] The active reductant is described as "cerium borohydride", which is generated in situ from NaBH 4 and CeCl 3 (H 2 O) 7 .
Carbonyl reduction, the net addition of H 2 across a carbon-oxygen double bond, is an important way to prepare alcohols. Stoichiometric reducing agents to accomplish this task include lithium aluminium hydride , sodium borohydride , alkoxy borohydrides, alkoxy aluminium hydrides, and boranes.
Many carboxylic acid: aldehyde redox reactions have a potential near this value 2 H + + 2 e − → H 2: −0.41 Non-zero value for the hydrogen potential because at pH = 7, [H +] = 10 −7 M and not 1 M as in the standard hydrogen electrode (SHE), and that: E red = -0.059 V × 7 = -0.41 V: NADP + + H + + 2e − → NADPH: −0.320 −0.370 The ...