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Nonoxynol-9 is a common ingredient of most vaginal and anal lubricants due to its spermicidal properties. A 2004 study found that over a six-month period, the typical-use failure rates for five nonoxynol-9 vaginal contraceptives (film, suppository, and gels at three different concentrations) ranged from 10% to 20%.
The most common active ingredient of spermicides is nonoxynol-9. Spermicides containing nonoxynol-9 are available in many forms, such as jelly (gel), films, and foams. Used alone, spermicides have a perfect use failure rate of 6% per year when used correctly and consistently, and 16% failure rate per year in typical use. [1]
Nonoxynol-9, a spermicide, is ineffective as a topical microbicide in preventing HIV infection. Although nonoxynol-9 has been shown to increase the risk of HIV infection when used frequently by women at high risk of infection, it remains a contraceptive option for women at low risk. [27]
Most spermicides, which come in films, foams and more, rely on a chemical, nonoxynol-9, which kills sperm by destroying their cellular membranes. Culwell expained that nonoxynol-9 can be dangerous ...
People sensitive to Nonoxynol-9, an ingredient in the spermicide used in the sponge, may experience unpleasant irritation and may face increase risk of sexually transmitted infections. Sponge users may have a slightly higher risk of toxic shock syndrome .
The most commonly discussed compound nonoxynol-9 is a spermicide, formulated primarily as a component of vaginal foams and creams. Nonoxynol was found to metabolize into free nonylphenol when administered to lab animals. [1] Arkopal-N60, with on average 6 ethylene glycol units is a related used surfactant.
For example, using condoms with spermicides the estimated perfect use failure rate would be comparable to the perfect use failure rate of the implant. [6] However, mathematically combining the rates to estimate the effectiveness of combined methods can be inaccurate, as the effectiveness of each method is not necessarily independent.
The section on other spermicides is rather poor. I will resist making changes since I don't know enough but it describes 2 alternatives (unless you count lactic acid), however the spermicides section lists 3. Furthermore it claims only octoxynol-9 is available in the US. This seems rather odd, is this really true?