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  2. Treating a dog's arthritis is often challenging because many dogs don't show signs of pain until they're older, vets said. After the condition has progressed to severe levels, owners often feel ...

  3. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Gabapentin reduces spasticity in multiple sclerosis and is prescribed as one of the first-line options. [53] It is an established treatment of restless legs syndrome. [54] Gabapentin alleviates itching in kidney failure (uremic pruritus) [55] [56] and itching of other causes. [57] It may be an option in essential or orthostatic tremor. [58] [59 ...

  4. Neurogenic claudication - Wikipedia

    en.wikipedia.org/wiki/Neurogenic_claudication

    Gabapentin aims to reduce pain and provide relief by altering the normal functioning of neurotransmitters that induce a sensation of pain and discomfort. [28] However, the exact mechanism of Gabapentin’s functioning in the body is not completely understood and current knowledge is based on experimental studies that target the nervous system ...

  5. Canine degenerative myelopathy - Wikipedia

    en.wikipedia.org/wiki/Canine_degenerative_myelopathy

    A dog with degenerative myelopathy often stands with its legs close together and may not correct an unusual foot position due to a lack of conscious proprioception. Canine degenerative myelopathy, also known as chronic degenerative radiculomyelopathy, is an incurable, progressive disease of the canine spinal cord that is similar in many ways to amyotrophic lateral sclerosis (ALS).

  6. Antiarthritics - Wikipedia

    en.wikipedia.org/wiki/Antiarthritics

    These symptoms may persist or occur periodically and if symptoms are not managed, major complications may develop including permanent joint changes, chronic pain, and functional disabilities. [7] Ultimately, antiarthritic treatments aim to achieve disease remission or low disease activity if remission cannot be achieved and thereby improving ...

  7. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    The oral bioavailability of gabapentin enacarbil (as gabapentin) is greater than or equal to 68%, across all doses assessed (up to 2,800 mg), with a mean of approximately 75%. [ 25 ] [ 1 ] In contrast to the other gabapentinoids, the pharmacokinetics of phenibut have been little-studied, and its oral bioavailability is unknown. [ 28 ]