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Around 2–3 centimetres (0.8–1.2 in) in length, [3] it is the lower narrower part of the uterus continuous above with the broader upper part—or body—of the uterus. [4] The lower end of the cervix bulges through the anterior wall of the vagina, and is referred to as the vaginal portion of cervix (or ectocervix) while the rest of the ...
The cervical canal is generally lined by "endocervical mucosa" which consists of a single layer of mucinous columnar epithelium. However, after menopause, the functional squamocolumnar junction moves into the cervical canal, and hence the distal part of the cervical canal may be lined by stratified squamous epithelium (conforming to a "type 3 transformation zone").
In this diagram, the canal of the cervix (or endocervix) is circled at the base of the womb. The vaginal portion of the cervix projects free into the vagina. The transformation zone , at the opening of the cervix into the vagina, is the area where most abnormal cell changes occur
Endocervical curettage is a medical procedure used to extract cells of the endocervix to visualize under a microscope. Direct cervical visualization, colposcopy, and even endocervical colposcopy are not enough to fully analyze all areas of the endocervical epithelium and thus endocervical curettage is the method of choice in cases where this is necessary.
The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
The FDA Compliant disposable SoftBiopsy can be used to biopsy the exocervix and lower genital tract during colposcopy or when a suspicious lesion is detected. Unlike the “sharp edge” biopsy design of gynecological biopsy devices, the SoftBiopsy design is intended to gently frictionally abrade and collect abundant trans-epithelial tissue ...
In regard to the cervix, squamous metaplasia can sometimes be found in the endocervix, as it is composed of simple columnar epithelium, whereas the ectocervix is composed of stratified squamous non-keratinized epithelium. [2]
The human brain. Differences in male and female brain size are relative to body size. [83] Early research into the differences between male and female brains showed that male brains are, on average, larger than female brains. This research was frequently cited to support the assertion that women are less intelligent than men.