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Phenylephrine is a selective α 1-adrenergic receptor agonist with minimal to no β-adrenergic receptor agonist activity or induction of norepinephrine release. [5] [8] [15] It causes constriction of both arteries and veins. [12] Phenylephrine was patented in 1933 [16] and came into medical use in 1938. [17] It is available as a generic medication.
Phenylephrine was originally approved by the FDA in 1976 based on reports that suggested the medication helped reduce congestion. Worth noting: The overwhelming “ evidence ” to support this ...
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It contains the following active ingredients (15 mL is one tablespoon, half the recommended adult dose): Acetaminophen (500 mg/15 mL) (pain reliever/fever reducer) Dextromethorphan (15 mg/15 mL) (cough suppressant) Doxylamine succinate (6.25 mg/15 mL) (antihistamine/hypnotic) Pseudoephedrine (30 mg/15 mL) (nasal decongestant)
CVS is removing some over-the-counter allergy and cold medicines from their shelves one month after an independent advisory committee to the US Food and Drug Administration declared that ...
Panadol Cold and Catarrh contains three active ingredients: paracetamol, phenylephrine hydrochloride as a nasal decongestant, and chlorpheniramine maleate to prevent certain allergies. [19] Panadol Cold and Flu and Panadol Fever and Congestion both combine paracetamol with phenylephrine hydrochloride as a nasal decongestant. [12] [26]