Search results
Results From The WOW.Com Content Network
Stanislao Cannizzaro FRS (/ ˌ k æ n ɪ ˈ z ɑːr oʊ / KAN-iz-AR-oh, [1] US also /-ɪ t ˈ s ɑːr-/-it-SAR-, [2] Italian: [staniˈzlaːo kannitˈtsaːro]; 13 July 1826 – 10 May 1910) was an Italian chemist. He is famous for the Cannizzaro reaction and for his influential role in the atomic-weight deliberations of the Karlsruhe Congress ...
In organic chemistry, the Mannich reaction is a three-component organic reaction that involves the amino alkylation of an acidic proton next to a carbonyl (C=O) functional group by formaldehyde (H−CHO) and a primary or secondary amine (−NH 2) or ammonia (NH 3). [1] The final product is a β-amino-carbonyl compound also known as a Mannich base.
In the Cannizzaro reaction, formaldehyde and base react to produce formic acid and methanol, ... (1.0 US fl oz) of 37% formaldehyde solution can cause death.
Neopentyl glycol is synthesized industrially by the aldol reaction of formaldehyde and isobutyraldehyde. This creates the intermediate hydroxypivaldehyde, which can be converted to neopentyl glycol by either a Cannizzaro reaction with excess formaldehyde, or by hydrogenation using palladium on carbon. [2]
Aldehyde structure. In organic chemistry, an aldehyde (/ ˈ æ l d ɪ h aɪ d /) is an organic compound containing a functional group with the structure R−CH=O. [1] The functional group itself (without the "R" side chain) can be referred to as an aldehyde but can also be classified as a formyl group.
In the context of butanol fuel, isobutyraldehyde is of interest as a precursor to isobutanol. E. coli as well as several other organisms has been genetically modified to produce isobutanol. α-Ketoisovalerate, derived from oxidative deamination of valine, is prone to decarboxylation to give isobutyraldehyde, which is susceptible to reduction to the alcohol: [3]
In general, glyoxylic acid undergoes an electrophilic aromatic substitution reaction with phenols, a versatile step in the synthesis of several other compounds. The immediate product with phenol itself is 4-hydroxymandelic acid. This species reacts with ammonia to give hydroxyphenylglycine, a precursor to the drug amoxicillin.
The reaction requires a strong Brønsted base and a weak Lewis acid, and gives a methanol coproduct: [1] (H 2 CO) 2 n + n B + n LA + n HArOH → n HC(=O)ArOH + n [HB][LA:OMe] Formally, it combines the Cannizzaro disproportionation with a directed Friedel-Crafts acylation .