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c. 2,200 per year (U.S.) [8] Alcohol intoxication, also known in overdose as alcohol poisoning, [1] commonly described as drunkenness or inebriation, [9] is the behavior and physical effects caused by a recent consumption of alcohol. [6][10] In addition to the toxicity of ethanol, the main psychoactive component of alcoholic beverages, other ...
In the US and many international publications, BAC levels are written as a percentage such as 0.08%, meaning that there is 0.08 g of alcohol for every 100 mL of blood. [1] [2] In different countries, the maximum permitted BAC when driving ranges from the limit of detection (zero tolerance) to 0.08%. [3] [2] BAC levels above 0.40% are ...
Alcohol binds to several different subtypes of GABA A, but not to others. The main subtypes responsible for the subjective effects of alcohol are the α 1 β 3 γ 2, α 5 β 3 γ 2, α 4 β 3 δ and α 6 β 3 δ subtypes, although other subtypes such as α 2 β 3 γ 2 and α 3 β 3 γ 2 are also affected. Activation of these receptors causes ...
Alcohol-related brain damage [1] [2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe , [ 3 ] limbic system , and cerebellum , [ 4 ] with widespread ...
Alcohol and health. Alcohol (also known as ethanol) has a number of effects on health. Short-term effects of alcohol consumption include intoxication and dehydration. Long-term effects of alcohol include changes in the metabolism of the liver and brain, with increased risk of several types of cancer and alcohol use disorder. [1]
Alcohol is the leading cause of direct deaths from drug overdoses. Symptoms of ethanol overdose may include nausea, vomiting, CNS depression, coma, acute respiratory failure, or death. Levels of even less than 0.1% can cause intoxication, with unconsciousness often occurring at 0.3–0.4%. [306]
Risk factors known as of 2010 are: Quantity of alcohol taken: Consumption of 60–80 g per day (14 g is considered one standard drink in the US, e.g. 1 + 1 ⁄ 2 US fl oz or 44 mL hard liquor, 5 US fl oz or 150 mL wine, 12 US fl oz or 350 mL beer; drinking a six-pack of 5% ABV beer daily would be 84 g and just over the upper limit) for 20 years or more in men, or 20 g/day for women ...
Alcoholic ketoacidosis (AKA) is a specific group of symptoms and metabolic state related to alcohol use. [3] Symptoms often include abdominal pain, vomiting, agitation, a fast respiratory rate, and a specific "fruity" smell. [2] Consciousness is generally normal. [1]