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Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. [7]
[1] [11] Celecoxib and parecoxib have a sulfonamide substituent (SO 2 NH 2) in para-position on one of the aryl rings while etoricoxib and rofecoxib have a methylsulfone (SO 2 CH 3). [12] The oxidation state on the sulfur is important for selectivity; sulfones and sulfonamides are selective for COX-2 but sulfoxides and sulfides are not.
Ciprofloxacin/celecoxib or PrimeC is a fixed-dose combination of ciprofloxacin and celecoxib developed for ALS. [1] [2] References This page was last edited on 15 ...
'The Hate U Give,' a critically acclaimed novel written by Angie Thomas, has been banned by the Katy Independent School District in Texas, which includes 15 junior high schools and eight high ...
Gov. Greg Abbott says banning the Chinese-owned video-sharing app is an opportunity for Texas to protect itself from cyber intrusions. But how does the ban work?
Celecoxib/tramadol sold under the brand name Seglentis, is a fixed-dose combination of the anti-inflammatory celecoxib and the opioid tramadol used for the management and treatment of pain. [ 1 ] Developed by Spanish pharmaceutical company Esteve , it was approved for medical use in the United States in October 2021.
In 2021, Abbott signed into law the “Lone Star Infrastructure Protection Act,” which the Texas legislature unanimously passed to ban Texas governmental entities and businesses from entering ...
The therapeutic recommended dosages were 12.5, 25, and 50 mg with an approximate bioavailability of 93%. [12] [13] [14] Rofecoxib crossed the placenta and blood–brain barrier, [12] [13] [15] and took 1–3 hours to reach peak plasma concentration with an effective half-life (based on steady-state levels) around 17 hours.