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  2. Aldosterone - Wikipedia

    en.wikipedia.org/wiki/Aldosterone

    An increase in sensed pressure results in an increased rate of firing by the baroreceptors and a negative feedback response, lowering systemic arterial pressure. Aldosterone release causes sodium and water retention, which causes increased blood volume, and a subsequent increase in blood pressure, which is sensed by the baroreceptors. [39]

  3. Renin–angiotensin system - Wikipedia

    en.wikipedia.org/wiki/Renin–angiotensin_system

    The renin-angiotensin system (RAS), or renin-angiotensin-aldosterone system (RAAS), is a hormone system that regulates blood pressure, fluid, and electrolyte balance, and systemic vascular resistance. [2][3] When renal blood flow is reduced, juxtaglomerular cells in the kidneys convert the precursor prorenin (already present in the blood) into ...

  4. Angiotensin - Wikipedia

    en.wikipedia.org/wiki/Angiotensin

    Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. It is part of the renin–angiotensin system, which regulates blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex to promote sodium retention by the kidneys. An oligopeptide, angiotensin is a hormone and a ...

  5. Renin - Wikipedia

    en.wikipedia.org/wiki/Renin

    Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin-angiotensin-aldosterone system (RAAS)—also known as the renin-angiotensin-aldosterone axis—that increases the volume of extracellular fluid (blood plasma, lymph, and interstitial fluid) and causes arterial ...

  6. Pathophysiology of hypertension - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of...

    Angiotensin II also causes the adrenal glands to release aldosterone, which stimulates the epithelial cells of the kidneys to increase re-absorption of salt and water, leading to raised blood volume and raised blood pressure. So elevated renin levels in the blood (normally 1.98-2.46 ng/ml in the upright position) [40] leads to hypertension. [2 ...

  7. Mineralocorticoid - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid

    Mineralocorticoid. Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones. Mineralocorticoids are produced in the adrenal cortex and influence salt and water balances (electrolyte balance and fluid balance). The primary mineralocorticoid is aldosterone.

  8. Sympathoadrenal system - Wikipedia

    en.wikipedia.org/wiki/Sympathoadrenal_system

    Overproduction of these molecules causes an increase in the production and release of the catecholamines, leading the cardiovascular system to become elevated in the systolic blood pressure and the diastolic blood pressure, along with the increase in the heart rate of the individual. [8]

  9. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Antihypertensive. Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). [1] Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can ...