Search results
Results From The WOW.Com Content Network
The sodium–potassium pump a critical enzyme for regulating sodium and potassium levels in cells. Potassium is the main intracellular ion for all types of cells, while having a major role in maintenance of fluid and electrolyte balance. [1] [2] Potassium is necessary for the function of all living cells and is thus present in all plant and ...
Potassium channels function to conduct potassium ions down their electrochemical gradient, doing so both rapidly (up to the diffusion rate of K + ions in bulk water) and selectively (excluding, most notably, sodium despite the sub-angstrom difference in ionic radius). [4] Biologically, these channels act to set or reset the resting potential in ...
An ATP-sensitive potassium channel (or K ATP channel) is a type of potassium channel that is gated by intracellular nucleotides, ATP and ADP. ATP-sensitive potassium channels are composed of K ir 6.x-type subunits and sulfonylurea receptor (SUR) subunits, along with additional components. [ 1 ]
BK channels (big potassium), are large conductance calcium-activated potassium channels, [1] also known as Maxi-K, slo1, or Kca1.1. BK channels are voltage-gated potassium channels that conduct large amounts of potassium ions (K + ) across the cell membrane , hence their name, big potassium .
Potassium channels are the most diverse group of the ion channel family. [ 2 ] [ 3 ] They are important in shaping the action potential, and in neuronal excitability and plasticity. [ 4 ] The potassium channel family is composed of several functionally distinct isoforms, which can be broadly separated into 2 groups: [ 5 ] the practically non ...
After the loss of TH+ (tyrosine hydroxylase-positive) substantia nigra compacta (SNc) neurons due to Parkinson’s-induced neurodegeneration, the number of these neurons can partially recover via a cell phenotype "shift" from TH- (tyrosine hydroxylase-negative) to TH+. The number of TH+ neurons can be altered by SK channel modulation; to be ...
K v 7.1 (KvLQT1) is a potassium channel protein whose primary subunit in humans is encoded by the KCNQ1 gene. [5] Its mutation causes Long QT syndrome, K v 7.1 is a voltage and lipid-gated potassium channel present in the cell membranes of cardiac tissue and in inner ear neurons among other tissues.
The recommended name for this protein is potassium voltage-gated channel subfamily A member 1 but a number of alternatives have been used in the literature including HuK1 (human K + channel I), RBK1 (rubidium potassium channel 1), MBK (mouse brain K + channel), voltage gated potassium channel HBK1, voltage gated potassium channel subunit K v 1.1, voltage-gated K + channel HuKI and AEMK ...