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Oseltamivir, sold under the brand name Tamiflu among others, is an antiviral medication used to treat and prevent influenza A and influenza B, viruses that cause the flu. [5] Many medical organizations recommend it in people who have complications or are at high risk of complications within 48 hours of first symptoms of infection. [ 6 ]
According to the CDC, [1] "a study published in the New England Journal of Medicine [25] [in August, 2014] indicated that the high-dose vaccine was 24.2% more effective in preventing flu in adults 65 years of age and older relative to a standard-dose vaccine." The CDC recommends the high-dose vaccine for people 65 and over but expresses no ...
[49] [50] [51] However, the use of the preparation has been described as "imprudent" when an influenza strain causes death in healthy adults by cytokine storm leading to primary viral pneumonia. [52] The manufacturer cites a lack of evidence for cytokine-related risks, but labels the product only as an antioxidant and food supplement .
Viral neuraminidases are essential for influenza reproduction, facilitating viral budding from the host cell. Oseltamivir (Tamiflu), zanamivir (Relenza), laninamivir (Inavir), and peramivir belong to this class. Unlike the M2 inhibitors, which work only against the influenza A virus, NAIs act against both influenza A and influenza B. [1] [2] [3 ...
Example Polish call for vaccination against diphtheria and tetanus Global vaccination coverage 1980 to 2019 among one year olds [1]. A vaccination schedule is a series of vaccinations, including the timing of all doses, which may be either recommended or compulsory, depending on the country of residence.
Rimantadine (INN, sold under the trade name Flumadine [1]) is an orally administered antiviral drug [2] used to treat, and in rare cases prevent, influenzavirus A infection. . When taken within one to two days of developing symptoms, rimantadine can shorten the duration and moderate the severity of influ
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Available evidence indicates that vaccinating the elderly with the high-dose vaccine leads to a stronger immune response against influenza than the regular-dose vaccine. [130] [131] [132] A flu vaccine containing an adjuvant was approved by the US Food and Drug Administration (FDA) in November 2015, for use by adults aged 65 years of age and ...