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  2. Scleroderma - Wikipedia

    en.wikipedia.org/wiki/Scleroderma

    Usual onset: Middle age [1] Types: Localized, systemic scleroderma [2] ... Scleroderma is a group of autoimmune diseases that may result in changes to the skin, ...

  3. Systemic scleroderma - Wikipedia

    en.wikipedia.org/wiki/Systemic_scleroderma

    The interval of peak onset starts at age 30 [49] and ends at age 50. [49] Globally, estimates of prevalence vary from 31.0 to 658.6 affected people per million. [48] Systemic sclerosis has a female:male ratio of 3:1 (8:1 in mid- to late childbearing years). Incidence is twice as high among African Americans.

  4. Morphea - Wikipedia

    en.wikipedia.org/wiki/Morphea

    Borrelia burgdorferi infection may be relevant for the induction of a distinct autoimmune type of scleroderma; it may be called "Borrelia-associated early onset morphea" and is characterized by the combination of disease onset at younger age, infection with B. burgdorferi, and evident autoimmune phenomena as reflected by high-titer antinuclear ...

  5. Scleromyositis - Wikipedia

    en.wikipedia.org/wiki/Scleromyositis

    Scleroderma can develop in every age group from infants to the elderly, but its onset is most frequent between the ages of 25 and 55. In most cases it is observed that the disease involves an overproduction of collagen.

  6. If You Notice This One Thing While You're Eating, Talk to ...

    www.aol.com/lifestyle/notice-one-thing-while...

    Dysphagia can happen at any age, with about 1 in 25 U.S. adults experiencing it every year, Dr. Abu-Ghanem says. It’s more common in older adults. ... Muscle disorders, such as scleroderma or ...

  7. Parry–Romberg syndrome - Wikipedia

    en.wikipedia.org/wiki/Parry–Romberg_syndrome

    The average age of onset is nine years of age, [4] ... Essakali HN, Mohcine Z (October 2005). "[Neuroretinitis, Parry-Romberg syndrome, and scleroderma]".

  8. CREST syndrome - Wikipedia

    en.wikipedia.org/wiki/CREST_syndrome

    CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.

  9. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    In untreated PPMS, the median time from onset to requiring a walking aid is estimated as seven years. [128] In SPMS, a 2014 cohort study reported that people required a walking aid after an average of five years from the onset of SPMS, and were chair or bed-bound after an average of fifteen years. [208]