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An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
[49] [50] When nebulized, budesonide has an bioavailability of 6% and reaches C max within 1–3 hours. [50] [49] When formulated as a rectal foam, budesonide has an bioavailability of 3% to 27% and reaches C max around 1.5 hours. [51] The plasma protein binding of budesonide is around 85-90%, with an apparent volume of distribution of 2.2-3.9L/kg.
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Budesonide/formoterol, sold under the brand name Symbicort among others, is a fixed-dose combination medication used in the management of asthma or chronic obstructive pulmonary disease (COPD). [2] It contains budesonide , a steroid ; and formoterol , a long-acting β 2 -agonist (LABA). [ 2 ]
When combined with inhaled steroids, β adrenoceptor agonists can improve symptoms. [1] [2] In children this benefit is uncertain and they may be potentially harmful. [2]They should not be used without an accompanying steroid due to an increased risk of severe symptoms, including exacerbation in both children and adults. [3]
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The dose values are divided by the maximum dose, referred to as d max, yielding a plot in terms of percentage of the maximum dose. Dose measurements are generally made in water or "water equivalent" plastic with an ionization chamber, since water is very similar to human tissue with regard to radiation scattering and absorption.