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An immature teratoma is a teratoma that contains anaplastic immature elements, and is often synonymous with malignant teratoma. [1] A teratoma is a tumor of germ cell origin, containing tissues from more than one germ cell line, [ 2 ] [ 3 ] [ 4 ] It can be ovarian or testicular in its origin.
Immature teratomas contain immature or embryonic tissue which significantly differentiates them from mature teratomas as they carry dermoid cysts. [5] It is commonly observed in 15 to 19-year-old women and rarely in women after menopause. [6] Immature teratomas are characterized with a diameter of 14–25 cm, encapsulated mass, cystic areas ...
Immature teratoma is the malignant counterpart of the mature teratoma and contains immature tissues which typically show primitive or embryonal neuroectodermal histopathology. Immature teratoma has one of the lowest rates of somatic mutation of any tumor type and results from one of five mechanisms of meiotic failure .
Sacrococcygeal teratomas are benign 75% of the time, malignant 12% of the time, and the remainder are considered "immature teratomas" that share benign and malignant features. Benign sacrococcygeal teratomas are more likely to develop in younger children who are less than 5 months old, and older children are more likely to develop malignant ...
Ovarian tumors, or ovarian neoplasms, are tumors in the ovary. [1] Not all are ovarian cancer. [1] They consist of mainly solid tissue, while ovarian cysts contain fluid. [2]In 2020, the World Health Organization (WHO) divided ovarian tumours as 90% epithelial, 3% germ cell, and 2% sex cord-stromal types.
There is no specific marker for immature teratomas, but carcinoembryonic antigen (CEA), CA-125, CA19-9, or AFP can sometimes indicate an immature teratoma. [ 32 ] Stage I teratomas make up the majority (75%) of cases and have the best prognosis, with 98% of patients surviving five years; if a Stage I tumor is also grade 1, it can be treated ...
Teratocarcinoma refers to a germ cell tumor that is a mixture of teratoma with embryonal carcinoma, or with choriocarcinoma, or with both. [9] This kind of mixed germ cell tumor may be known simply as a teratoma with elements of embryonal carcinoma or choriocarcinoma, or simply by ignoring the teratoma component and referring only to its ...
Nongerminomatous germ-cell tumors may be associated with increased markers such as alpha-fetoprotein with yolk sac tumors, as well as embryonic cell carcinomas and immature teratomas and beta-HCG, which occur in choriocarcinomas. In one to 15% of germinomas, a low level of beta-HCG may be produced.