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It was discovered in 2000 as one of two improved mutants by H. Bujard and his colleagues after random mutagenesis of the Tet repressor part of the transactivator gene. [6] Tet-On 3G (also known as rtTA-V10 [7]) is similar to Tet-On Advanced but was derived from rtTA2 S-S2 rather than rtTA2 S-M2. It is also human codon optimized and composed of ...
Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene.Its function, regulation, and utilizable pathways remain a matter of current research while it seems to be involved in DNA demethylation and therefore gene regulation, [5] [6] but is expressed as different isoforms which may have distinct functions.
Tet Repressor proteins (otherwise known as TetR) are proteins playing an important role in conferring antibiotic resistance to large categories of bacterial species. Tetracycline (Tc) is a broad family of antibiotics to which bacteria have evolved resistance.
194388 Ensembl ENSG00000187605 ENSMUSG00000034832 UniProt O43151 Q8BG87 RefSeq (mRNA) NM_001287491 NM_001366022 NM_183138 NM_001347313 RefSeq (protein) NP_001274420 NP_001352951 NP_001334242 NP_898961 Location (UCSC) Chr 2: 73.98 – 74.11 Mb Chr 6: 83.34 – 83.44 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Tet methylcytosine dioxygenase 3 is a protein that in humans is encoded ...
54790 214133 Ensembl ENSG00000168769 ENSMUSG00000040943 UniProt Q6N021 Q4JK59 RefSeq (mRNA) NM_001127208 NM_017628 NM_001040400 NM_145989 NM_001346736 RefSeq (protein) NP_001120680 NP_060098 NP_001035490 NP_001333665 Location (UCSC) Chr 4: 105.15 – 105.28 Mb Chr 3: 133.17 – 133.25 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Tet methylcytosine dioxygenase 2 (TET2) is a human ...
CIITA is a human gene which encodes a protein called the class II, major histocompatibility complex, transactivator. [5] Mutations in this gene are responsible for the bare lymphocyte syndrome in which the immune system is severely compromised and cannot effectively fight infection . [ 5 ]
Gene conversion is the process by which one DNA sequence replaces a homologous sequence such that the sequences become identical after the conversion. [1] Gene conversion can be either allelic , meaning that one allele of the same gene replaces another allele, or ectopic , meaning that one paralogous DNA sequence converts another.
LTR retrotransposons have direct long terminal repeats that range from ~100 bp to over 5 kb in size. LTR retrotransposons are further sub-classified into the Ty1-copia-like (Pseudoviridae), Ty3-like (Metaviridae, formally referred to as Gypsy-like, a name that is being considered for retirement [4]), and BEL-Pao-like (Belpaoviridae) groups based on both their degree of sequence similarity and ...