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SimThyr is a free continuous dynamic simulation program for the pituitary-thyroid feedback control system. [1] The open-source program is based on a nonlinear model of thyroid homeostasis. [ 2 ] [ 3 ] [ 4 ] In addition to simulations in the time domain the software supports various methods of sensitivity analysis .
The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is a butterfly-shaped gland located in the neck below the Adam's apple. It consists of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the isthmus (pl.: isthmi).
Thyroid is a medical journal in the field of endocrinology, covering research on diseases of the thyroid. It is the official journal of the American Thyroid Association and published by Mary Ann Liebert, Inc.
Euthyroidism: Normal thyroid function; Hypothyroidism: Reduced thyroid function primary hypothyroidism: Feedback loop interrupted by low thyroid secretory capacity, e.g. after thyroid surgery or in case of autoimmune thyroiditis; secondary hypothyroidism: Feedback loop interrupted on the level of pituitary, e.g. in anterior pituitary failure
Amiodarone inhibits peripheral conversion of thyroxine to triiodothyronine; also interferes with thyroid hormone action. [citation needed] Lithium inhibits thyroid hormone release. [citation needed] Phenobarbitone, phenytoin, carbamazepine, rifampin induce metabolic degradation of triiodothyronine (T 3) and thyroxine (T 4). [citation needed]
Iodine deficiency is a lack of the trace element iodine, an essential nutrient in the diet.It may result in metabolic problems such as goiter, sometimes as an endemic goiter as well as congenital iodine deficiency syndrome due to untreated congenital hypothyroidism, which results in developmental delays and other health problems.
Thyroid follicular cells form a simple cuboidal epithelium and are arranged in spherical thyroid follicles surrounding a fluid filled space known as the colloid. The interior space formed by the follicular cells is known as the follicular lumen .
Barry John Durrant-Peatfield (November 1936 – 27 August 2023) was a British medical practitioner specialising in metabolic disorders namely, hypothyroidism.. Durrant-Peatfield submitted to voluntary erasure from the medical register as an alternative to having his license suspended for the use of unapproved diagnostic tests and treatments such as whole thyroid extracts (NDT).