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CTE is preferred for the examination of Crohn's disease due to its increased spatial resolution and better ability to examine the wall of the small intestine than traditional CT studies of the abdomen and pelvis. [5] Findings on CTE that indicate active inflammation in the small bowel, possibly caused by Crohn's disease, include:
The association between inflammatory conditions of the eye and Crohn's disease is due to many Crohn's disease patients having genetic markers such as HLA-B07, HLA-B27 and HLA-DRB1*0103. [57] Additionally, cytokines IL-6, IL-10, and IL-17 which are produced in the bowel enter the circulatory system and travel to the eyes to trigger inflammation.
Diagnostic findings Crohn's disease Ulcerative colitis Terminal ileum involvement: Commonly: Seldom Colon involvement: Usually: Always Rectum involvement: Seldom: Usually (95%) [1] Involvement around the anus: Common [2] Seldom Bile duct involvement: No increase in rate of primary sclerosing cholangitis: Higher rate [3] Distribution of disease
In Crohn's disease, surgery involves removing the worst inflamed segments of the intestine and connecting the healthy regions, but unfortunately, it does not cure Crohn's or eliminate the disease. At some point after the first surgery, Crohn's disease can recur in the healthy parts of the intestine, usually at the resection site. [76] (For ...
Acute abdomen is a condition where there is a sudden onset of severe abdominal pain requiring immediate recognition and management of the underlying cause. [7] The underlying cause may involve infection, inflammation , vascular occlusion or bowel obstruction.
Gross pathology of normal colon (left) and severe ulcerative colitis (right), forming pseudopolyps (smaller than the cobblestoning typically seen in Crohn's disease), over a continuous area (rather than skip lesions of Crohn's disease), and with a relatively gradual transition from normal colon (while Crohn's is typically more abrupt).
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