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Parvovirus B19 is a cause of chronic anemia in individuals with immunodeficiency, receiving immunosuppressive therapy or with HIV infection. Treatment with intravenous immunoglobulin usually resolves the anemia although relapse can occur.
Fifth disease, also known as erythema infectiosum and slapped cheek syndrome, [3] is a common and contagious disease caused by infection with parvovirus B19. [4] This virus was discovered in 1975 and can cause other diseases besides fifth disease. [5]
Human parvovirus B19, also known as "slapped cheek disease," is on the rise in the United States, especially among young children. The highly contagious respiratory infection is usually mild in ...
Parvovirus B19 is transmitted through droplets from symptomatic people and from infected people who don’t show any signs of infection. The virus appears to be spreading this summer based on a ...
According to the CDC, the parvovirus B19 infection rate was less than a 3% in all age groups from 2022 to June 2024. Then in June, the infection rate suddenly jumped to 10%.
B19 infection is often asymptomatic but can manifest in a variety of ways, including Fifth disease with its characteristic rash in children, persistent anemia in immunocompromised persons and in people who have underlying hemoglobinopathies, [20] transient aplastic crises, hydrops fetalis in pregnant women, and arthropathy. Human bocavirus 1 is ...
Parvovirus B19 can also spread through blood or blood products, though infection through transfusion is rare. In addition, pregnant people who are infected can spread the virus to their unborn child.
Parvovirus B19 Infection and Transient Aplastic Crisis [5] The majority of TAC are triggered by Parvovirus B19 in patients with hematologic disorders. These patients often present with high viral titers during profound anemia and are found to have reticulocytopenia upon further evaluation.