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Nausea and vomiting are common side effects when first beginning therapy with apomorphine; [18] antiemetics such as trimethobenzamide or domperidone, dopamine antagonists, [19] are often used while first starting apomorphine. Around 50% of people grow tolerant enough to apomorphine's emetic effects that they can discontinue the antiemetic.
apomorphine – emetic (used to induce vomiting) artificial tears – lubricant eye drops used as a tear supplement; atenolol – treats cardiac arrhythmias, hypertension, and diabetes plus other cardiovascular disorders; atipamezole – α 2-adrenergic antagonist used to reverse the sedative and analgesic effects of alpha-2 adrenergic receptor ...
Side effects in dogs and cats include hypersalivation, diarrhea, loss of appetite, and vomiting. [ 12 ] [ 16 ] Eight percent of dogs taking maropitant at doses meant to prevent motion sickness vomited right after, likely due to the local effects maropitant had on the gastrointestinal tract.
This list of dog diseases is a selection of diseases and other conditions found in the dog. Some of these diseases are unique to dogs or closely related species, while others are found in other animals, including humans. Not all of the articles listed here contain information specific to dogs.
Around 1970 clinicians started using the dopamine agonist apomorphine alongside L-DOPA to minimize the side effects caused by L-DOPA, the dopamine agonists bind to the dopamine receptor in the absence of dopamine. Apomorphine had limited use since it had considerable side effects and difficulty with administration.
Less-common side effects can include excess air or gas in your stomach, burping, heartburn, indigestion, fast heartbeat, low blood sugar, low energy and fatigue, or even gallstones, Dr. Comite says.
N-n-Propylnorapomorphine (NPA) is an aporphine derivative dopamine agonist closely related to apomorphine. [2] [3] In rodents it has been shown to produce hyperactivity, stereotypy, hypothermia, antinociception, and penile erection, among other effects.
Most dogs, however, will need radiation, chemotherapy, and other medications. Even with those therapies, the survival time is short, so ivermectin could help if it proves to be useful.