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  2. Pharmacokinetics of progesterone - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics_of...

    Progesterone is used as part of hormone replacement therapy in people who have low progesterone levels, and for other reasons. For purposes of comparison with normal physiological circumstances, luteal phase levels of progesterone are 4 to 30 ng/mL, while follicular phase levels of progesterone are 0.02 to 0.9 ng/mL, menopausal levels are 0.03 to 0.3 ng/mL, and levels of progesterone in men ...

  3. Menopause - Wikipedia

    en.wikipedia.org/wiki/Menopause

    [10] [2] At the physiological level, menopause happens because of a decrease in the ovaries' production of the hormones estrogen and progesterone. [1] While typically not needed, measuring hormone levels in the blood or urine can confirm a diagnosis. [11] Menopause is the opposite of menarche, the time when periods start. [12]

  4. Antiprogestogen - Wikipedia

    en.wikipedia.org/wiki/Antiprogestogen

    Progestins, including progesterone, are vital for preparing the uterus for the implantation of a fertilized egg during the luteal phase of the menstrual cycle. If fertilization, implantation, and other events necessary for pregnancy occur, increased progestin (i.e., progesterone) levels are essential in maintaining the pregnancy.

  5. Mifepristone - Wikipedia

    en.wikipedia.org/wiki/Mifepristone

    A single preovulatory 10-mg dose of mifepristone delays ovulation by three to four days and is as effective an emergency contraceptive as a single 1.5-mg dose of the progestin levonorgestrel. [55] In women, mifepristone at doses greater or equal to 1 mg/kg antagonizes the endometrial and myometrial effects of progesterone.

  6. Hormone replacement therapy - Wikipedia

    en.wikipedia.org/wiki/Hormone_replacement_therapy

    Progesterone is the main female sex hormone that occurs naturally and is also manufactured into a drug that is used in menopausal hormone therapy. [1] Although both classes of hormones can have symptomatic benefit, progestogen is specifically added to estrogen regimens, unless the uterus has been removed, to avoid the increased risk of ...

  7. Hormone Therapy Was Villainized For Decades. Now, It ... - AOL

    www.aol.com/hormone-therapy-villainized-decades...

    Women’s estrogen and progesterone levels plummet. (They fluctuate wildly during the two to eight years before menopause, known as perimenopause.) Hormone therapy aims to supplement those levels ...

  8. Pharmacodynamics of progesterone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Progesterone is a progestogen, or an agonist of the nuclear progesterone receptors (PRs), the PR-A, PR-B, and PR-C. [1] In one study, progesterone showed EC 50 Tooltip half-maximal effective concentration values of 7.7 nM for the human PR-A and 8.0 nM for the human PR-B. [5] In addition to the PRs, progesterone is an agonist of the membrane progesterone receptors (mPRs), including the mPRα ...

  9. Menstrual cycle - Wikipedia

    en.wikipedia.org/wiki/Menstrual_cycle

    Menstrual cycle The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the ...