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Aromatase deficiency is a rare condition characterized by extremely low levels or complete absence of the enzyme aromatase activity in the body. [2] It is an autosomal recessive disease resulting from various mutations of gene CYP19 (P450arom) which can lead to ambiguous genitalia and delayed puberty in females, continued linear growth into adulthood and osteoporosis in males and virilization ...
Estrogen insensitivity syndrome (EIS), or estrogen resistance, is a form of congenital estrogen deficiency or hypoestrogenism [2] which is caused by a defective estrogen receptor (ER) – specifically, the estrogen receptor alpha (ERα) – that results in an inability of estrogen to mediate its biological effects in the body. [3]
Hyperestrogenism can be caused by ovarian tumors, [2] genetic conditions such as aromatase excess syndrome (also known as familial hyperestrogenism), or overconsumption of exogenous sources of estrogen, including medications used in hormone replacement therapy and hormonal contraception. [3]
Dog owners are now using holistic treatments to treat their pups, holistic veterinarians and canine researchers told ABC News. Whether used as preventative care, in tandem with Western medicine or ...
Aromatase (EC 1.14.14.14), also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1 , a member of the cytochrome P450 superfamily, which are monooxygenases that catalyze many reactions involved in steroidogenesis .
5α-Reductase 2 deficiency (5αR2D) is an autosomal recessive condition caused by a mutation in SRD5A2, a gene encoding the enzyme 5α-reductase type 2 (5αR2). People with this condition are genetically male, with one X and one Y chromosome in each cell, and they have testes .
Dr. Mark answers a pet owner's question about a dog with limping and dragging legs. ... Vet-Approved Home Treatment for Senior Dogs with Arthritis. Dr. Mark dos Anjos. December 27, 2024 at 5:05 AM ...
Macroorchidism is related to IGFS1 deficiency, which causes an increase in the secretion of follicle stimulating hormone (FSH). There are other causes for macroorchidism, such as hypothyroidism, local tumors, and aromatase deficiency. [3] Macroorchidism can be diagnosed by measuring the testicular volume using a prader orchidometer. [4]