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  2. Nucleic acid double helix - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_double_helix

    The double-helix model of DNA structure was first published in the journal Nature by James Watson and Francis Crick in 1953, [6] (X,Y,Z coordinates in 1954 [7]) based on the work of Rosalind Franklin and her student Raymond Gosling, who took the crucial X-ray diffraction image of DNA labeled as "Photo 51", [8] [9] and Maurice Wilkins, Alexander Stokes, and Herbert Wilson, [10] and base-pairing ...

  3. A-DNA - Wikipedia

    en.wikipedia.org/wiki/A-DNA

    A-DNA is one of the possible double helical structures which DNA can adopt. A-DNA is thought to be one of three biologically active double helical structures along with B-DNA and Z-DNA . It is a right-handed double helix fairly similar to the more common B-DNA form, but with a shorter, more compact helical structure whose base pairs are not ...

  4. DNA - Wikipedia

    en.wikipedia.org/wiki/DNA

    Here, the single-stranded DNA curls around in a long circle stabilized by telomere-binding proteins. [68] At the very end of the T-loop, the single-stranded telomere DNA is held onto a region of double-stranded DNA by the telomere strand disrupting the double-helical DNA and base pairing to one of the two strands.

  5. Base pair - Wikipedia

    en.wikipedia.org/wiki/Base_pair

    The size of an individual gene or an organism's entire genome is often measured in base pairs because DNA is usually double-stranded. Hence, the number of total base pairs is equal to the number of nucleotides in one of the strands (with the exception of non-coding single-stranded regions of telomeres ).

  6. Extrachromosomal circular DNA - Wikipedia

    en.wikipedia.org/wiki/Extrachromosomal_circular_DNA

    Extrachromosomal circular DNA (eccDNA) is a type of double-stranded circular DNA structure that was first discovered in 1964 by Alix Bassel and Yasuo Hotta. [1] In contrast to previously identified circular DNA structures (e.g., bacterial plasmids, mitochondrial DNA, circular bacterial chromosomes, or chloroplast DNA), eccDNA are circular DNA found in the eukaryotic nuclei of plant and animal ...

  7. Nucleic acid structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure

    Double-stranded RNA forms an A-type helical structure, unlike the common B-type conformation taken by double-stranded DNA molecules. The secondary structure of RNA consists of a single polynucleotide. Base pairing in RNA occurs when RNA folds between complementarity regions. Both single- and double-stranded regions are often found in RNA molecules.

  8. Nucleic acid tertiary structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_tertiary...

    Three DNA conformations are believed to be found in nature, A-DNA, B-DNA, and Z-DNA. The "B" form described by James D. Watson and Francis Crick is believed to predominate in cells. [ 2 ] James D. Watson and Francis Crick described this structure as a double helix with a radius of 10 Å and pitch of 34 Å , making one complete turn about its ...

  9. Nucleic acid thermodynamics - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_thermodynamics

    Nucleic acid thermodynamics is the study of how temperature affects the nucleic acid structure of double-stranded DNA (dsDNA). The melting temperature (T m) is defined as the temperature at which half of the DNA strands are in the random coil or single-stranded (ssDNA) state. T m depends on the length of the DNA molecule and its specific ...