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In organic chemistry, Fehling's solution is a chemical reagent used to differentiate between water-soluble carbohydrate and ketone (>C=O) functional groups, and as a test for reducing sugars and non-reducing sugars, supplementary to the Tollens' reagent test. The test was developed by German chemist Hermann von Fehling in 1849. [1]
Known as Fehling's solution it is a solution of copper sulfate mixed with alkali and potassium sodium tartrate (Rochelle salt). He was a contributor to the Handwörterbuch of Liebig, Friedrich Wöhler and Johann Christian Poggendorff , and to the Graham-Otto Textbook of Chemistry .
Fehling's solution was used for many years as a diagnostic test for diabetes, a disease in which blood glucose levels are dangerously elevated by a failure to produce enough insulin (type 1 diabetes) or by an inability to respond to insulin (type 2 diabetes). Measuring the amount of oxidizing agent (in this case, Fehling's solution) reduced by ...
It is an ingredient of Fehling's solution (reagent for reducing sugars). It is used in electroplating, in electronics and piezoelectricity, and as a combustion accelerator in cigarette paper (similar to an oxidizer in pyrotechnics). [2]
The nature of the complex formed in Fehling's solution is [Cu(L-tartH-2) 2] 6-(tart = tartrate) Therefore, all hydroxyl groups are deprotonated and the ball and stick model showed in the article is false. Moreover, L-tartaric acid is used to prepare Fehling's solution, so the citation of the publication dealing with complex compounds of copper ...
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Specifically, using Benedict's reagent and Fehling's solution the presence of the sugar is signaled by a color change from blue Cu(II) to reddish copper(I) oxide. [4] Schweizer's reagent and related complexes with ethylenediamine and other amines dissolve cellulose. [5] Amino acids such as cystine form very stable chelate complexes with copper(II).
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